Immature Survival Data From Early Trial Termination – Theory and Hta Practice
نویسندگان
چکیده
منابع مشابه
Immature Survival Data From Early Trial Termination - Theory and Hta Practice.
• As surrogate outcomes are often considered the primary endpoint(s) in oncology trials, these RCTs may not be powered and/or patients may not be followed-up long enough to allow detection of OS gains. While this approach may have been agreed upon with regulatory agencies as a requirement to obtain marketing authorisation, healthcare payers usually tend to have a greater focus on hard endpoints...
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ژورنال
عنوان ژورنال: Value in Health
سال: 2014
ISSN: 1098-3015
DOI: 10.1016/j.jval.2014.08.1971